Road traffic injuries are a major cause of death and disability globally, with a disproportionate number occurring in developing countries. Road traffic injuries are currently ranked ninth globally among the leading causes of disability adjusted life years lost, and the ranking is projected to rise to third by 2020. In 1998, developing countries accounted for more than 85% of all deaths due to road traffic crashes globally and for 96% of all children killed. Moreover, about 90% of the disability adjusted life years lost worldwide due to road traffic injuries occur in developing countries. The problem is increasing at a fast rate in developing countries due to rapid motorisation and other factors. However, public policy responses to this epidemic have been muted at national and international levels. Policy makers need to recognise this growing problem as a public health crisis and design appropriate policy responses.